Dr. Qinghua Xu
Associate Professor
School of Pharmaceutical Sciences
South-Central Minzu University, Wuhan, China
E-mail: xuqh@scuec.edu.cn
Education
2007.09 - 2011.07: B.S. in Basic Chemistry, Collage of Chemistry and Molecular Sciences, Wuhan University
2011.09 - 2016.12: Ph.D. in Polymer Chemistry and Physics, Changchun Institute of Applied Chemistry, Chinese Academy of Sciences
Professional Experiences
2023.10 – present: Associate Professor, School of Pharmaceutical Sciences, South-central Minzu University
2022. 11 - 2023.09: Assistant Professor, School of Materials Science and Engineering, Hubei University
2020.02 - 2022.05: Postdoctoral Associate, Davidson School of Chemical Engineering, Purdue University
2017.06 - 2020.01: Postdoctoral Associate, Department of Fiber Science & Apparel Design, Cornell University
Research Interests
[1] Design of bioactive hydrogels and their applications in three-dimensional cell culture, tissue engineering and drug delivery
[2] Preparation of stimuli responsive nanoparticles for controlled drug delivery
Selected Recent Publicaions
[1] Mazin H Hakim, Brian H Jun, Adib Ahmadzadegan, Paulina M Babiak, Qinghua Xu, Kevin P Buno, Julie C Liu, Arezoo M Ardekani, Pavlos P Vlachos*, Luis Solorio*. Investigation of macromolecular transport through tunable collagen hyaluronic acid matrices. Colloids and Surfaces B: Biointerfaces, 222 (2023) 113123.
[2] Qinghua Xu*, Jessica E. Torres, Mazin Hakim, Paulina M. Babiak, Pallabi Pal, Carly M. Battitoni, Michael Nguyen, Alyssa Panitch, Luis Solorio, Julie Liu*. Collagen- and hyaluronic acid-based hydrogels and their biomedical applications. Materials Science and Engineering R, 146 (2021) 100641.
[3] Qinghua Xu, Chih-Chang Chu*. A novel Pseudo-protein-based ROS-responsive nanoparticle for anticancer drug delivery. Journal of Biomedical Materials Research Part A, 2021, 109A: 524-537.
[4] Hiu Yee Kwan, Qinghua Xu, Ruihong Gong, Zhaoxiang Bian, Chih-Chang Chu. Targeted Chinese medicine delivery by a new family of biodegradable pseudo-protein nanoparticles for treating triple-negative breast cancer: in vitro and in vivo study. Frontiers in Oncology, 2020 (10), 600298.
[5] Zhen Zhang, Chaoliang He, Qinghua Xu, Xiuli Zhuang, Xuesi Chen. Preparation of Poly (L-glutamic acid)-based Hydrogels via Diels-Alder Reaction and Study on Their Biomolecule-responsive Properties. ACTA POLYMERICA SINICA, 2018 (1) 99-108.
[6] Qinghua Xu, Chaoliang He*, Chunsheng Xiao, Xuesi Chen*. Injectable polypeptide hydrogel as biomimetic scaffolds with tunable bioactivity and controllable cell adhesion. Biomacromolecules, 2017, 18 (4), 1411–1418.
[7] Qinghua Xu, Chaoliang He*, Zhen Zhang, Kaixuan Ren, Xuesi Chen*. Injectable, biomolecule-responsive polypeptide hydrogels with triggered degradation capacity for cell encapsulation and facile cell recovery. ACS Applied Materials & Interfaces, 2016, 8 (45), 30692-30702.
[8] Qinghua Xu, Chaoliang He*, Kaixuan Ren, Chunsheng Xiao, Xuesi Chen*. Thermosensitive polypeptide hydrogels as a platform for ROS-triggered cargo release with innate cytoprotective ability under oxidative stress. Advanced Healthcare Materials, 2016, 5 (15); 1979-1990.
[9] Qinghua Xu, Chaoliang He*, Chunsheng Xiao, and Xuesi Chen*. Reactive oxygen species (ROS) responsive polymers for biomedical applications. Macromolecular Bioscience, 2016; 16 (5); 635-646.
[10] Qinghua Xu, Chaoliang He*, Chunsheng Xiao, Shuangjiang Yu and Xuesi Chen*. ε-Methacryloyl-L-lysine based polypeptides and their thiol-ene click functionalization. Polymer Chemistry, 2015; 6; 1758-1767.